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OptoBio Introduction
  • University of Michigan spin-off, founded in 2015
  • Family and Friends funding ($2 million)
  • One exclusive license from the University of Michigan (issued)
  • 5 additional pending patents owned by Optofluidic Bioassay
  • Two product families:
    • MicroFluere® microplate for ELISA – commercial ready by June, 2021
      • For high throughput applications, e.g., clinical labs, hospitals and research use
    • Xpress ELISA system – longer term but much larger market opportunity
      • Point-Of-Care-Testing, e.g., urgent care centers, clinics, doctors’ offices
      • Further miniaturization => Personal ELISA
      • Additional development to be funded by non-dilutive grants and MicroFluere ® commercialization
  • Covid-19 antibody testing natural entry – high throughput, low cost

IP Status

  • 10730044, Assay Plate and Uses Thereof, 10730044 (issued in 2020)
  • 62657834, Differential Pressure Assisted Drainage System (pending)
  • PCT/US20/52631, Microfluidic structure for bio-assay using absorption or colorimetric methods (pending)
  • 63/001,366, Methods for enzyme-linked immunosorbent assay (ELISA) using microfluidic plate (pending)
  • US 2019/0383750 A1, OPTOFLUIDIC DIAGNOSTICS SYSTEM (pending)
  • Two additional patent applications (to be submitted)

Our Publications in Express ELISA

  • X. Tan et al., “Rapid Mouse Follicle Stimulating Hormone Quantification and Estrus Cycle Analysis Using an Automated Microfluidic Chemiluminescent ELISA System,” ACS Sens. 3, 2327-2334 (2018).
  • X. Tan et al., “Multiparameter Urine Analysis for Quantitative Bladder Cancer Surveillance of Orthotopic Xenografted Mice,” Lab Chip 20, 634-646 (2020).
  • W. Xue et al., “Rapid and sensitive detection of drugs of abuse in sweat by multiplexed capillary based immuno-biosensors,” Analyst 145, 1346-1354 (2020).
  • X. Tan, “Dissertation: The Development of an Optofluidic Biosensing Platform for Multifunctional Biomolecular Analysis,” in Biomedical Engineering Department (University of Michigan, 2020).
  • X. Tan et al., “Rapid and quantitative detection of SARS-CoV-2 specific IgG for convalescent serum evaluation,” Biosensors and Bioelectronics 169, 112572 (2020)
  • X. Tan et al., “Quantification and Immunoprofiling of Bladder Cancer Cell-Derived Extracellular Vesicles with Microfluidic Chemiluminescent ELISA,” (to be submitted)